Michelangelo Puglisi was born in 1879 in Catania, Sicily. His father, Giuseppe Reale Puglisi, was the founder of one of the largest Italian factories for the manufacture of stringed instruments and he introduced his children to the business. Michelangelo often worked alongside his brother, Concetto Puglisi. In 1914, Puglisi took over the business side of his family’s business, and in 1919, after the death of his father, he became director of the firm. Michelangelo was an active maker and produced many fine instruments, including violins, guitars, and mandolins, and also instructed his son Giuseppe in the craft. The Puglisi factory was destroyed by bombing in 1943, but was later rebuilt.